Cardiac Toxicity Associated with Capecitabine Therapy
نویسندگان
چکیده
منابع مشابه
Unanticipated toxicity to capecitabine.
A 63-year-old African American woman, L.L., was diagnosed with hormone-negative, HER2-negative, stage IIIa breast cancer 18 months ago. Following a left modified radical mastectomy with immediate reconstruction, L.L. was treated with dose-dense adriamycincyclophosphamide followed by paclitaxel. Follow-up visits were uneventful until a month ago, when she reported persistent right-upper quadrant...
متن کاملErosive Pressure Dermatitis Associated with Cardiac Pacemaker
Erosive dermatitis is a skin reaction associated with implantable cardiac devices (ie, pacemakers and cardioverter defibrillators). We report a 65-year-old man with a history of several cerebrovascular attacks who developed an erythematous crusted erosive patch over the pacemaker site after implantation of two subsequent pacemakers. We suggest that physical irritation may be a trigger factor fo...
متن کاملTacrolimus toxicity associated with concomitant metoclopramide therapy.
Subtherapeutic tacrolimus trough concentrations were noted in a 52-year-old woman who had undergone liver transplantation. Her tacrolimus dosage was increased from 7 to 28 mg twice/day, and ketoconazole therapy was added; however, her tacrolimus concentration remained undetectable. Metoclopramide 10 mg 4 times/day was begun to control the patient's new-onset nausea and vomiting. Within 48 hours...
متن کاملParalytic ileus associated with capecitabine.
Paralytic ileus is a temporary arrest of intestinal peristalsis. We report on two patients with breast cancer who developed paralytic ileus following treatment with capecitabine. The pathophysiology of this disorder and its possible connection to capecitabine are described with the aim of promoting the early recognition of the clinical picture so that unnecessary surgery can be avoided.
متن کاملHypokalemia secondary to capecitabine: a hidden toxicity?
BACKGROUND Hyopkalemia is a listed toxicity in the capecitabine (Xeloda(R); Roche, Nutley, NJ) package insert. However, the incidence and severity of this toxicity is not known. METHODS We performed a retrospective evaluation of hypokalemia in 77 patients, who received capecitabine for gastrointestinal malignancies between April 2002 and November 2004. Hypokalemia was defined as K(+) level <3...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Oncologica
سال: 2003
ISSN: 0284-186X,1651-226X
DOI: 10.1080/02841860310011861